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Proceedings Paper

Effect of surface topographic features on the optical properties of skin: a phantom study
Author(s): Guangli Liu; Jianfeng Chen; Zuhua Zhao; Gang Zhao; Erbao Dong; Jiaru Chu; Ronald X. Xu
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Paper Abstract

Tissue-simulating phantoms are used to validate and calibrate optical imaging systems and to understand light transport in biological tissue. Light propagation in a strongly turbid medium such as skin tissue experiences multiple scattering and diffuse reflection from the surface. Surface roughness introduces phase shifts and optical path length differences for light which is scattered within the skin tissue and reflected from the surface. In this paper, we study the effect of mismatched surface roughness on optical measurement and subsequent determination of optical properties of skin tissue. A series of phantoms with controlled surface features and optical properties corresponding to normal human skin are fabricated. The fabrication of polydimethylsiloxane (PDMS) phantoms with known surface roughness follows a standard soft lithography process. Surface roughness of skin-simulating phantoms are measured with Bruker stylus profiler. The diffuse reflectance of the phantom is validated by a UV/VIS spectrophotometer. The results show that surface texture and roughness have considerable influence on the optical characteristics of skin. This study suggests that surface roughness should be considered as an important contributing factor for the determination of tissue optical properties.

Paper Details

Date Published: 31 October 2016
PDF: 7 pages
Proc. SPIE 10024, Optics in Health Care and Biomedical Optics VII, 100240O (31 October 2016); doi: 10.1117/12.2247656
Show Author Affiliations
Guangli Liu, Univ. of Science and Technology of China (China)
Jianfeng Chen, Univ. of Science and Technology of China (China)
Zuhua Zhao, Univ. of Science and Technology of China (China)
Gang Zhao, Univ. of Science and Technology of China (China)
Erbao Dong, Univ. of Science and Technology of China (China)
Jiaru Chu, Univ. of Science and Technology of China (China)
Ronald X. Xu, Univ. of Science and Technology of China (China)
The Ohio State Univ. (United States)


Published in SPIE Proceedings Vol. 10024:
Optics in Health Care and Biomedical Optics VII
Qingming Luo; Xingde Li; Ying Gu; Yuguo Tang, Editor(s)

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