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Proceedings Paper

A microfluidic laser scattering sensor for label-free detection of waterborne pathogens
Author(s): Huang Wei; Limei Yang; Feng Li
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Paper Abstract

A microfluidic-based multi-angle laser scattering (MALS) sensor capable of acquiring scattering pattern of single particle is demonstrated. The size and relative refractive index (RI) of polystyrene (PS) microspheres were deduced with accuracies of 60 nm and 0.001 by analyzing the scattering patterns. We measured scattering patterns of waterborne parasites i.e., cryptosporidium parvum (c.parvum) and giardia lamblia (g.lamblia), and some other representative species in 1 L water within 1 hour, and the waterborne parasites were identified with accuracy better than 96% by classification of distinctive scattering patterns with a support-vector-machine (SVM) algorithm. The system provides a promising tool for label-free and rapid detection of waterborne parasites.

Paper Details

Date Published: 25 October 2016
PDF: 6 pages
Proc. SPIE 10156, Hyperspectral Remote Sensing Applications and Environmental Monitoring and Safety Testing Technology, 101561E (25 October 2016); doi: 10.1117/12.2246993
Show Author Affiliations
Huang Wei, Suzhou Institute of Nano-Tech and Nano-Bionics (China)
Limei Yang, Suzhou Institute of Nano-Tech and Nano-Bionics (China)
Feng Li, Suzhou Institute of Nano-Tech and Nano-Bionics (China)


Published in SPIE Proceedings Vol. 10156:
Hyperspectral Remote Sensing Applications and Environmental Monitoring and Safety Testing Technology

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