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Proceedings Paper

Improving the signal-to-noise ratio in ultrasound-modulated optical tomography by a lock-in amplifier
Author(s): Lili Zhu; Jingping Wu; Guimin Lin; Liangjun Hu; Hui Li
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Paper Abstract

With high spatial resolution of ultrasonic location and high sensitivity of optical detection, ultrasound-modulated optical tomography (UOT) is a promising noninvasive biological tissue imaging technology. In biological tissue, the ultrasound-modulated light signals are very weak and are overwhelmed by the strong unmodulated light signals. It is a difficulty and key to efficiently pick out the weak modulated light from strong unmodulated light in UOT. Under the effect of an ultrasonic field, the scattering light intensity presents a periodic variation as the ultrasonic frequency changes. So the modulated light signals would be escape from the high unmodulated light signals, when the modulated light signals and the ultrasonic signal are processed cross correlation operation by a lock-in amplifier and without a chopper. Experimental results indicated that the signal-to-noise ratio of UOT is significantly improved by a lock-in amplifier, and the higher the repetition frequency of pulsed ultrasonic wave, the better the signal-to-noise ratio of UOT.

Paper Details

Date Published: 31 October 2016
PDF: 7 pages
Proc. SPIE 10024, Optics in Health Care and Biomedical Optics VII, 100244O (31 October 2016); doi: 10.1117/12.2246676
Show Author Affiliations
Lili Zhu, Fujian Normal Univ. (China)
Jingping Wu, Fujian Normal Univ. (China)
Guimin Lin, Fujian Normal Univ. (China)
Liangjun Hu, Fujian Normal Univ. (China)
Hui Li, Fujian Normal Univ. (China)


Published in SPIE Proceedings Vol. 10024:
Optics in Health Care and Biomedical Optics VII
Qingming Luo; Xingde Li; Ying Gu; Yuguo Tang, Editor(s)

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