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Proceedings Paper

In vivo hyperspectral imaging and differentiation of skin cancer
Author(s): Larisa A. Zherdeva; Ivan A. Bratchenko; Oleg O. Myakinin; Alexander A. Moryatov; Sergey V. Kozlov; Valery P. Zakharov
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Paper Abstract

Results of hyperspectral imaging analysis for in vivo visualization of skin neoplasms are presented. 16 melanomas, 19 basal cell carcinomas and 10 benign tumors with different stages of neoplasm growth were tested. The HSI system provide skin tissue images with 5 nm spectral resolution in the range of 450-750 nm with automatic stabilization of each frame compensating displacement of the scanning area due to spontaneous macro-movements of the patient. The integrated optical densities in 530-600 and 600-670 nm ranges are used for real-time hemoglobin and melanin distribution imaging in skin tissue. It was shown that the total accuracy of skin cancer identification exceeds 90% and 70% for differentiation of melanomas from BCC and begihn tumors. It was demonstrated the possibility for HSI classification of melanomas of different stages.

Paper Details

Date Published: 31 October 2016
PDF: 8 pages
Proc. SPIE 10024, Optics in Health Care and Biomedical Optics VII, 100244G (31 October 2016); doi: 10.1117/12.2246433
Show Author Affiliations
Larisa A. Zherdeva, Samara National Research Univ. (Russian Federation)
Ivan A. Bratchenko, Samara National Research Univ. (Russian Federation)
Oleg O. Myakinin, Samara National Research Univ. (Russian Federation)
Alexander A. Moryatov, Samara State Medical Univ. (Russian Federation)
Sergey V. Kozlov, Samara State Medical Univ. (Russian Federation)
Valery P. Zakharov, Samara National Research Univ. (Russian Federation)


Published in SPIE Proceedings Vol. 10024:
Optics in Health Care and Biomedical Optics VII
Qingming Luo; Xingde Li; Ying Gu; Yuguo Tang, Editor(s)

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