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Proceedings Paper

Polymer microfluidic bioreactor fabrication by means of gray scale lithography technique
Author(s): Andrzej Sierakowski; Piotr Prokaryn; Rafał Dobrowolski; Anna Malinowska; Dariusz Szmigiel; Piotr Grabiec; Damian Trojanowski; Dagmara Jakimowicz; Jolanta Zakrzewska-Czerwinska
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Paper Abstract

In this paper we present a new method of polymer microfluidic bioreactor fabrication by means of a gray scale lithography technique. As a result of the gray scale lithography process the 3D model of the bioreactor is defined in photoresist. The obtained model serves as a sacrificial layer for the subsequent transfer of the 3D shape into the polymer material. The proposed method allows simultaneous definition of both the overall bioreactor geometry and the multi steps cell traps in a single photolithography step. Such microfluidic structure can be used for sorting cells based on their size. The developed solution significantly simplifies the production technology and reduces its costs in comparison to standard photolithography techniques.

Paper Details

Date Published: 10 November 2016
PDF: 10 pages
Proc. SPIE 10161, 14th International Conference on Optical and Electronic Sensors, 1016106 (10 November 2016); doi: 10.1117/12.2245033
Show Author Affiliations
Andrzej Sierakowski, Institute of Electron Technology (Poland)
Piotr Prokaryn, Institute of Electron Technology (Poland)
Rafał Dobrowolski, Institute of Electron Technology (Poland)
Anna Malinowska, Institute of Electron Technology (Poland)
Dariusz Szmigiel, Institute of Electron Technology (Poland)
Piotr Grabiec, Institute of Electron Technology (Poland)
Damian Trojanowski, Univ. of Wrocław (Poland)
Dagmara Jakimowicz, Univ. of Wrocław (Poland)
Jolanta Zakrzewska-Czerwinska, Univ. of Wrocław (Poland)

Published in SPIE Proceedings Vol. 10161:
14th International Conference on Optical and Electronic Sensors
Piotr Jasiński, Editor(s)

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