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Proceedings Paper

Measurements of vitamin B12 in human blood serum using resonance Raman spectroscopy
Author(s): G. Tsiminis; E. P. Schartner; J. L. Brooks; M. R. Hutchinson
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Paper Abstract

Vitamin B12 (cobalamin and its derivatives) deficiency has been identified as a potential modifiable risk factor for dementia and Alzheimer’s disease. Chronic deficiency of vitamin B12 has been significantly associated with an increased risk of cognitive decline. An effective and efficient method for measuring vitamin B12 concentration in human blood would enable ongoing tracking and assessment of this potential modifiable risk factor. In this work we present an optical sensor based on resonance Raman spectroscopy for rapid measurements of vitamin B12 in human blood serum. The measurement takes less than a minute and requires minimum preparation (centrifuging) of the collected blood samples.

Paper Details

Date Published: 9 December 2016
PDF: 4 pages
Proc. SPIE 10013, SPIE BioPhotonics Australasia, 100130M (9 December 2016); doi: 10.1117/12.2244620
Show Author Affiliations
G. Tsiminis, ARC Ctr. of Excellence for Nanoscale BioPhotonics (Australia)
The Univ. of Adelaide (Australia)
E. P. Schartner, ARC Ctr. of Excellence for Nanoscale BioPhotonics (Australia)
The Univ. of Adelaide (Australia)
J. L. Brooks, The Univ. of Adelaide (Australia)
M. R. Hutchinson, ARC Ctr. of Excellence for Nanoscale BioPhotonics (Australia)
The Univ. of Adelaide (Australia)


Published in SPIE Proceedings Vol. 10013:
SPIE BioPhotonics Australasia
Mark R. Hutchinson; Ewa M. Goldys, Editor(s)

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