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Proceedings Paper

Towards high throughput cell barcoding using intracellular whispering gallery modes
Author(s): Avinash Upadhya; Matjaž Humar; Seok-Hyun Yun
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Paper Abstract

• Current approaches to cellular tagging are based on labelling via inherently broad emission spectra of fluorescent molecules and other such methods. • This complicates applications to individual cell identification and reduces the number of cells that can be distinguished reliably. • Whispering Gallery Mode (WGM) Microresonators have major advantages compared to current tagging methods. They have successfully been implanted within and used to tag cells attached to a substrate (Humar and Yun, 2015). • We aimed to extend this to free flowing cells through microfluidic devices. • We demonstrate the successful preliminary tagging of approximately 128 cells thus far and suggest methods for improvement.

Paper Details

Date Published:
PDF: 1 pages
Proc. SPIE 10013, SPIE BioPhotonics Australasia, 100132O; doi: 10.1117/12.2244614
Show Author Affiliations
Avinash Upadhya, The Australian National Univ. (Australia)
Matjaž Humar, Harvard Univ. (United States)
Jožef Stefan Institute (Slovenia)
Univ. of Ljubljana (Slovenia)
Seok-Hyun Yun, Harvard Univ. (United States)
Wellman Ctr. for Photomedicine (United States)
Harvard-MIT Health Sciences and Technology (United States)

Published in SPIE Proceedings Vol. 10013:
SPIE BioPhotonics Australasia
Mark R. Hutchinson; Ewa M. Goldys, Editor(s)

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