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Proceedings Paper

Hemoglobin concentration determination based on near infrared spatially resolved transmission spectra
Author(s): Linna Zhang; Gang Li; Ling Lin
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Paper Abstract

Spatially resolved diffuse reflectance spectroscopy method has been proved to be more effective than single point spectroscopy method in the experiment to predict the concentration of the Intralipid diluted solutions. However, Intralipid diluted solution is simple, cannot be the representative of turbid liquids. Blood is a natural and meaningful turbid liquid, more complicate. Hemoglobin is the major constituent of the whole blood. And hemoglobin concentration is commonly used in clinical medicine to diagnose many diseases. In this paper, near infrared spatially resolved transmission spectra (NIRSRTS) and Partial Least Square Regression (PLSR) were used to predict the hemoglobin concentration of human blood. The results showed the prediction ability for hemoglobin concentration of the proposed method is better than single point transmission spectroscopy method. This paper demonstrated the feasibility of the spatially resolved diffuse reflectance spectroscopy method for practical liquid composition analysis. This research provided a new thinking of practical turbid liquid composition analysis.

Paper Details

Date Published: 31 October 2016
PDF: 10 pages
Proc. SPIE 10024, Optics in Health Care and Biomedical Optics VII, 100241O (31 October 2016); doi: 10.1117/12.2243796
Show Author Affiliations
Linna Zhang, Tianjin Univ. (China)
Gang Li, Tianjin Univ. (China)
Ling Lin, Tianjin Univ. (China)


Published in SPIE Proceedings Vol. 10024:
Optics in Health Care and Biomedical Optics VII
Qingming Luo; Xingde Li; Ying Gu; Yuguo Tang, Editor(s)

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