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Proceedings Paper

Dual-wavelength retinal image registration based on vessel segmentation and optic disc detection
Author(s): Yong-li Xian; Yun Dai; Chun-ming Gao; Rui Du
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Paper Abstract

The dual-wavelength retinal image registration is one of the critical steps in the spectrophotometric measurements of oxygen saturation in the retinal vasculature. The dual-wavelength images (570 nm and 600 nm) are simultaneously captured by dual-wavelength retinal oximeter based on commercial fundus camera. The retinal oxygen saturation is finally measured after vessel segmentation, image registration and calculation of optical density ratio of the two images. Because the dual-wavelength images are acquired from different optical path, it is necessary to go through image registration before they are used to analyze the oxygen saturation. This paper presents a new approach to dual-wavelength retinal image registration based on vessel segmentation and optic disc detection. Firstly, the multi-scale segmentation algorithm based on the Hessian matrix is used to realize vessel segmentation. Secondly, after optic disc is detected by convergence index filter and the center of the optic disc is obtained by centriod algorithm, the translational difference between the images can be determined. The center of the optic disc is used as the center of rotation, and the registration based on mutual information can be achieved using contour and gray information of vessels through segmented image. So the rotational difference between the images can be determined too. The result shows that the algorithm can provide an accurate registration for the dual-wavelength retinal image.

Paper Details

Date Published: 27 September 2016
PDF: 10 pages
Proc. SPIE 9684, 8th International Symposium on Advanced Optical Manufacturing and Testing Technologies: Optical Test, Measurement Technology, and Equipment, 968417 (27 September 2016); doi: 10.1117/12.2243587
Show Author Affiliations
Yong-li Xian, Key Lab. of Adaptive Optics (China)
Univ. of Electronic Science and Technology of China (China)
Institute of Optics and Electronics (China)
Yun Dai, Key Lab. of Adaptive Optics (China)
Institute of Optics and Electronics (China)
Chun-ming Gao, Univ. of Electronic Science and Technology of China (China)
Rui Du, Key Lab. of Adaptive Optics (China)
Institute of Optics and Electronics (China)


Published in SPIE Proceedings Vol. 9684:
8th International Symposium on Advanced Optical Manufacturing and Testing Technologies: Optical Test, Measurement Technology, and Equipment
Yudong Zhang; Fan Wu; Ming Xu; Sandy To, Editor(s)

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