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Proceedings Paper

Whole organic electronic synapses for dopamine detection
Author(s): Martina Giordani; Michele Di Lauro; Marcello Berto; Carlo A. Bortolotti; Dominique Vuillaume; Henrique L. Gomes; Michele Zoli; Fabio Biscarini
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Paper Abstract

A whole organic artificial synapse has been fabricated by patterning PEDOT:PSS electrodes on PDMS that are biased in frequency to yield a STP response. The timescale of the STP response is shown to be sensitive to the concentration of dopamine, DA, a neurotransmitter relevant for monitoring the development of Parkinson’s disease and potential locoregional therapies. The sensitivity of the sensor towards DA has been validated comparing signal variation in the presence of DA and its principal interfering agent, ascorbic acid, AA. The whole organic synapse is biocompatible, soft and flexible, and is attractive for implantable devices aimed to real-time monitoring of DA concentration in bodily fluids. This may open applications in chronic neurodegenerative diseases such as Parkinson’s disease.

Paper Details

Date Published: 27 September 2016
PDF: 7 pages
Proc. SPIE 9944, Organic Sensors and Bioelectronics IX, 99440P (27 September 2016); doi: 10.1117/12.2239532
Show Author Affiliations
Martina Giordani, Univ. degli Studi di Modena e Reggio Emilia (Italy)
Michele Di Lauro, Univ. degli Studi di Modena e Reggio Emilia (Italy)
Marcello Berto, Univ. degli Studi di Modena e Reggio Emilia (Italy)
Carlo A. Bortolotti, Univ. degli Studi di Modena e Reggio Emilia (Italy)
National Research Council, CNR-NANO (Italy)
Dominique Vuillaume, Univ. of Lille, CNRS (France)
Henrique L. Gomes, Univ. do Algarve (Portugal)
Instituto de Telecomunicações (Portugal)
Michele Zoli, Univ. degli Studi di Modena e Reggio Emilia (Italy)
Fabio Biscarini, Univ. degli Studi di Modena e Reggio Emilia (Italy)


Published in SPIE Proceedings Vol. 9944:
Organic Sensors and Bioelectronics IX
Ioannis Kymissis; Ruth Shinar; Luisa Torsi, Editor(s)

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