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Proceedings Paper

Nanoparticles and nanostructured carriers for drug delivery and contrast enhancement
Author(s): Olga S. Godage; Alla B. Bucharskaya; Nikita A. Navolokin; Sergey V. German; Viktor V. Zuev; Georgy S. Terentyuk; Galina N. Maslyakova; Dmitry A. Gorin
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Paper Abstract

Currently, nanotechnologies are widely used in science and industry. It is known that the application of drug delivery nanostructured carriers for biomedicine is one of the promising areas of nanotechnology. Nanostructured carriers can be used in the diagnosis process for detecting a neoplastic tumor cells in peripheral blood, for contrast enhancement on magnetic resonance imaging (MRI), as well as for targeted drug delivery to tumor tissues. Agents for the targeted delivery (nanoparticles, liposomes, microcapsules, and etc) can affect the healthy tissues and organs, cause side effects and have a toxic effect. Therefore, it necessary to study the morphological changes that occur not only in the "target", such as a tumor, but also the internal organs, taking place under the influence of both the agents for targeted drug delivery and physical impact induced remote controlled drug release. Thus , the aim of our work is selection of the most promising agents for targeted drug delivery to tumor and contrast agents for in vivo visualization of tumor tissue boundaries , as well as their impact on the organs and tissues as results of nanostructured object biodistribution.

Paper Details

Date Published: 21 April 2016
PDF: 7 pages
Proc. SPIE 9917, Saratov Fall Meeting 2015: Third International Symposium on Optics and Biophotonics and Seventh Finnish-Russian Photonics and Laser Symposium (PALS), 99171H (21 April 2016); doi: 10.1117/12.2229872
Show Author Affiliations
Olga S. Godage, Saratov State Medical Univ. (Russian Federation)
Alla B. Bucharskaya, Saratov State Medical Univ. (Russian Federation)
Nikita A. Navolokin, Saratov State Medical Univ. (Russian Federation)
Sergey V. German, Saratov State Univ. (Russian Federation)
Viktor V. Zuev, Saratov State Medical Univ. (Russian Federation)
Georgy S. Terentyuk, Saratov State Medical Univ. (Russian Federation)
Saratov State Univ. (Russian Federation)
Galina N. Maslyakova, Saratov State Medical Univ. (Russian Federation)
Dmitry A. Gorin, Saratov State Univ. (Russian Federation)


Published in SPIE Proceedings Vol. 9917:
Saratov Fall Meeting 2015: Third International Symposium on Optics and Biophotonics and Seventh Finnish-Russian Photonics and Laser Symposium (PALS)
Elina A. Genina; Valery V. Tuchin; Vladimir L. Derbov; Dmitry E. Postnov; Igor V. Meglinski; Kirill V. Larin; Alexander Borisovich Pravdin, Editor(s)

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