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Proceedings Paper

The delayed luminescence spectroscopy as tool to investigate the cytotoxic effect on human cancer cells of drug-loaded nanostructured lipid carrier
Author(s): R. Grasso; M. Gulino; A. Scordino; F. Musumeci; A. Campisi; R. Bonfanti; C. Carbone; G. Puglisi
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Paper Abstract

The first results concerning the possibility to use Delayed Luminescence spectroscopy to evaluate the in vitro induction of cytotoxic effects on human glioblastoma cells of nanostructured lipid carrier and drug-loaded nanostructured lipid carrier are showed in this contribution. We tested the effects of nanostructured lipid carrier, ferulic acid and ferulic acidloaded nanostructured lipid carrier on U-87MG cell line. The study seems to confirm the ability of Delayed Luminescence to be sensible indicator of alterations induced on functionality of the mitochondrial respiratory chain complex I in U-87MG cancer cells when treated with nanostructured lipid carriers.

Paper Details

Date Published: 9 May 2016
PDF: 10 pages
Proc. SPIE 9887, Biophotonics: Photonic Solutions for Better Health Care V, 988723 (9 May 2016); doi: 10.1117/12.2227514
Show Author Affiliations
R. Grasso, Univ. degli Studi di Catania (Italy)
Istituto Nazionale di Fisica Nucleare (Italy)
M. Gulino, Kore Univ. (Italy)
Istituto Nazionale di Fisica Nucleare (Italy)
A. Scordino, Univ. degli Studi di Catania (Italy)
Istituto Nazionale di Fisica Nucleare (Italy)
F. Musumeci, Univ. degli Studi di Catania (Italy)
Istituto Nazionale di Fisica Nucleare (Italy)
A. Campisi, Univ. degli Studi di Catania (Italy)
R. Bonfanti, Univ. degli Studi di Catania (Italy)
C. Carbone, Univ. degli Studi di Catania (Italy)
G. Puglisi, Univ. degli Studi di Catania (Italy)


Published in SPIE Proceedings Vol. 9887:
Biophotonics: Photonic Solutions for Better Health Care V
Jürgen Popp; Valery V. Tuchin; Dennis L. Matthews; Francesco Saverio Pavone, Editor(s)

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