Share Email Print
cover

Proceedings Paper

Effect of pH on the morphology of kidney stones
Author(s): Neelesh Agarwal; Stacey Sova; N. B. Singh; Brad Arnold; Fow-Sen Choa; Brian Cullum; Ching-Hua Su
Format Member Price Non-Member Price
PDF $14.40 $18.00

Paper Abstract

The process for the formation of kidney stone is very complex phenomena and has some similarity to the crystal growth from a solution. It is very much dependent on the acidity pH of the fluids. This pH variation affects the content and amount of filtering residue and its morphology. In this study we have performed experiments using carbonate, oxides and urea to simulate and understand the morphologies of the residue filtered and coarsened in different conditions. We observed that different of morphologies of kidney stones can be explained on the basis of acidity and hydration conditions. At lower pH fat prism crystals are observed and as pH increases, long fat needle crystals with large aspect ratio are observed. The coarsening experiments showed further growth of crystals. The remelting experiments showed that during dissolution of kidney stones the joining material breaks first leaving the large faceted crystals undissolved when attempts are made to dissolve into small crystallites.

However, the morphology did not change. It was also observed that impurities such as magnesium oxide (MgO) affect the morphology significantly.

Paper Details

Date Published: 13 May 2016
PDF: 8 pages
Proc. SPIE 9863, Smart Biomedical and Physiological Sensor Technology XIII, 986303 (13 May 2016); doi: 10.1117/12.2219939
Show Author Affiliations
Neelesh Agarwal, Univ. of Maryland, Baltimore County (United States)
Stacey Sova, Univ. of Maryland, Baltimore County (United States)
N. B. Singh, Univ. of Maryland, Baltimore County (United States)
Brad Arnold, Univ. of Maryland, Baltimore County (United States)
Fow-Sen Choa, Univ. of Maryland, Baltimore County (United States)
Brian Cullum, Univ. of Maryland, Baltimore County (United States)
Ching-Hua Su, NASA Marshall Space Flight Ctr. (United States)


Published in SPIE Proceedings Vol. 9863:
Smart Biomedical and Physiological Sensor Technology XIII
Brian M. Cullum; Douglas Kiehl; Eric S. McLamore, Editor(s)

© SPIE. Terms of Use
Back to Top