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Proceedings Paper

Using ultrasound tomography to identify the distributions of density throughout the breast
Author(s): Mark Sak; Neb Duric; Peter Littrup; Mark E. Sherman; Gretchen L. Gierach
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Paper Abstract

Women with high breast density are at increased risk of developing breast cancer. Breast density has usually been defined using mammography as the ratio of fibroglandular tissue to total breast area. Ultrasound tomography (UST) is an emerging modality that can also be used to measure breast density. UST creates tomographic sound speed images of the patient’s breast which is useful as sound speed is directly proportional to tissue density. Furthermore, the volumetric and quantitative information contained in the sound speed images can be used to describe the distribution of breast density. The work presented here measures the UST sound speed density distributions of 165 women with negative screening mammography. Frequency distributions of the sound speed voxel information were examined for each patient. In a preliminary analysis, the UST sound speed distributions were averaged across patients and grouped by various patient and density-related factors (e.g., age, body mass index, menopausal status, average mammographic breast density). It was found that differences in the distribution of density could be easily visualized for different patient groupings. Furthermore, findings suggest that the shape of the distributions may be used to identify participants with varying amounts of dense and non-dense tissue.

Paper Details

Date Published: 1 April 2016
PDF: 11 pages
Proc. SPIE 9790, Medical Imaging 2016: Ultrasonic Imaging and Tomography, 979019 (1 April 2016); doi: 10.1117/12.2217611
Show Author Affiliations
Mark Sak, Delphinus Medical Technologies (United States)
Neb Duric, Delphinus Medical Technologies (United States)
Peter Littrup, Delphinus Medical Technologies (United States)
Brown Univ. (United States)
Mark E. Sherman, National Cancer Institute (United States)
Gretchen L. Gierach, National Cancer Institute (United States)


Published in SPIE Proceedings Vol. 9790:
Medical Imaging 2016: Ultrasonic Imaging and Tomography
Neb Duric; Brecht Heyde, Editor(s)

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