Share Email Print
cover

Proceedings Paper

Motion correction for improving the accuracy of dual-energy myocardial perfusion CT imaging
Author(s): Jed D. Pack; Zhye Yin; Guanglei Xiong; Priya Mittal; Simon Dunham; Kimberly Elmore; Peter M. Edic; James K. Min
Format Member Price Non-Member Price
PDF $14.40 $18.00

Paper Abstract

Coronary Artery Disease (CAD) is the leading cause of death globally [1]. Modern cardiac computed tomography angiography (CCTA) is highly effective at identifying and assessing coronary blockages associated with CAD. The diagnostic value of this anatomical information can be substantially increased in combination with a non-invasive, low-dose, correlative, quantitative measure of blood supply to the myocardium. While CT perfusion has shown promise of providing such indications of ischemia, artifacts due to motion, beam hardening, and other factors confound clinical findings and can limit quantitative accuracy. In this paper, we investigate the impact of applying a novel motion correction algorithm to correct for motion in the myocardium. This motion compensation algorithm (originally designed to correct for the motion of the coronary arteries in order to improve CCTA images) has been shown to provide substantial improvements in both overall image quality and diagnostic accuracy of CCTA. We have adapted this technique for application beyond the coronary arteries and present an assessment of its impact on image quality and quantitative accuracy within the context of dual-energy CT perfusion imaging. We conclude that motion correction is a promising technique that can help foster the routine clinical use of dual-energy CT perfusion. When combined, the anatomical information of CCTA and the hemodynamic information from dual-energy CT perfusion should facilitate better clinical decisions about which patients would benefit from treatments such as stent placement, drug therapy, or surgery and help other patients avoid the risks and costs associated with unnecessary, invasive, diagnostic coronary angiography procedures.

Paper Details

Date Published: 29 March 2016
PDF: 7 pages
Proc. SPIE 9788, Medical Imaging 2016: Biomedical Applications in Molecular, Structural, and Functional Imaging, 97880Z (29 March 2016); doi: 10.1117/12.2216986
Show Author Affiliations
Jed D. Pack, GE Global Research (United States)
Zhye Yin, GE Global Research (United States)
Guanglei Xiong, Weill Cornell Medical College (United States)
Dalio Institute of Cardiovascular Imaging (United States)
Priya Mittal, Weill Cornell Medical College (United States)
Dalio Institute of Cardiovascular Imaging (United States)
Simon Dunham, Weill Cornell Medical College (United States)
Dalio Institute of Cardiovascular Imaging (United States)
Kimberly Elmore, Weill Cornell Medical College (United States)
Dalio Institute of Cardiovascular Imaging (United States)
Peter M. Edic, GE Global Research (United States)
James K. Min, Weill Cornell Medical College (United States)
Dalio Institute of Cardiovascular Imaging (United States)


Published in SPIE Proceedings Vol. 9788:
Medical Imaging 2016: Biomedical Applications in Molecular, Structural, and Functional Imaging
Barjor Gimi; Andrzej Krol, Editor(s)

© SPIE. Terms of Use
Back to Top