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Proceedings Paper

Validation of coded aperture coherent scatter spectral imaging for normal and neoplastic breast tissues via surgical pathology
Author(s): R. E. Morris; K. E. Albanese; M. N. Lakshmanan; S. J. McCall; J. A. Greenberg; A. J. Kapadia
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Paper Abstract

This study intends to validate the sensitivity and specificity of coded aperture coherent scatter spectral imaging (CACSSI) by comparison to standard histological preparation and pathologic analysis methods used to differentiate normal and neoplastic breast tissues. A composite overlay of the CACSSI rendered image and pathologist interpreted stained sections validate the ability of CACSSI to differentiate normal and neoplastic breast structures ex-vivo. Via comparison to pathologist annotated slides, the CACSSI system may be further optimized to maximize sensitivity and specificity for differentiation of breast carcinomas.

Paper Details

Date Published: 22 March 2016
PDF: 9 pages
Proc. SPIE 9783, Medical Imaging 2016: Physics of Medical Imaging, 97835T (22 March 2016); doi: 10.1117/12.2216974
Show Author Affiliations
R. E. Morris, Duke Univ. Medical Ctr. (United States)
K. E. Albanese, Duke Univ. Medical Ctr. (United States)
M. N. Lakshmanan, Duke Univ. Medical Ctr. (United States)
S. J. McCall, Duke Univ. Medical Ctr. (United States)
J. A. Greenberg, Duke Univ. (United States)
A. J. Kapadia, Duke Univ. Medical Ctr. (United States)


Published in SPIE Proceedings Vol. 9783:
Medical Imaging 2016: Physics of Medical Imaging
Despina Kontos; Thomas G. Flohr, Editor(s)

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