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Proceedings Paper

Predicting detection performance with model observers: Fourier domain or spatial domain?
Author(s): Baiyu Chen; Lifeng Yu; Shuai Leng; James Kofler; Christopher Favazza; Thomas Vrieze; Cynthia McCollough
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Paper Abstract

The use of Fourier domain model observer is challenged by iterative reconstruction (IR), because IR algorithms are nonlinear and IR images have noise texture different from that of FBP. A modified Fourier domain model observer, which incorporates nonlinear noise and resolution properties, has been proposed for IR and needs to be validated with human detection performance. On the other hand, the spatial domain model observer is theoretically applicable to IR, but more computationally intensive than the Fourier domain method. The purpose of this study is to compare the modified Fourier domain model observer to the spatial domain model observer with both FBP and IR images, using human detection performance as the gold standard. A phantom with inserts of various low contrast levels and sizes was repeatedly scanned 100 times on a third-generation, dual-source CT scanner at 5 dose levels and reconstructed using FBP and IR algorithms. The human detection performance of the inserts was measured via a 2-alternative-forced-choice (2AFC) test. In addition, two model observer performances were calculated, including a Fourier domain non-prewhitening model observer and a spatial domain channelized Hotelling observer. The performance of these two mode observers was compared in terms of how well they correlated with human observer performance. Our results demonstrated that the spatial domain model observer correlated well with human observers across various dose levels, object contrast levels, and object sizes. The Fourier domain observer correlated well with human observers using FBP images, but overestimated the detection performance using IR images.

Paper Details

Date Published: 30 March 2016
PDF: 8 pages
Proc. SPIE 9783, Medical Imaging 2016: Physics of Medical Imaging, 978326 (30 March 2016); doi: 10.1117/12.2216962
Show Author Affiliations
Baiyu Chen, Mayo Clinic (United States)
Lifeng Yu, Mayo Clinic (United States)
Shuai Leng, Mayo Clinic (United States)
James Kofler, Mayo Clinic (United States)
Christopher Favazza, Mayo Clinic (United States)
Thomas Vrieze, Mayo Clinic (United States)
Cynthia McCollough, Mayo Clinic (United States)


Published in SPIE Proceedings Vol. 9783:
Medical Imaging 2016: Physics of Medical Imaging
Despina Kontos; Thomas G. Flohr, Editor(s)

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