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Proceedings Paper

Investigating relationships between left atrial volume, symmetry, and sphericity
Author(s): Prahlad G. Menon; Sotiris Nedios; Gerhard Hindricks; Andreas Bollmann
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Paper Abstract

Catheter ablation is a safe and effective therapy for drug-refractory patients symptomatic of atrial fibrillation (AF), with up to 80% of patients experiencing long-term arrhythmia-free survival. However, up to 20–40% of patients require more than one procedure in order to become arrhythmia-free. Therefore, appropriate patient selection is paramount to the effective implementation and long-term success of ablation therapy for patients with atrial fibrillation (AF). In this study, as a precursor to evaluating clinical significance of specific LA shape metrics as pre-procedural predictors of AF recurrence following ablative pulmonary vein isolation therapy, we report on a computational geometric analysis in a pilot cohort evaluating relationships between various patient-specific metrics of LA shape which might have such predictive value. This study specifically is focused on establishing the relationship between LA volume and sphericity, using a novel methodology for computing atrial sphericity based on regional shape.

Paper Details

Date Published: 29 March 2016
PDF: 5 pages
Proc. SPIE 9788, Medical Imaging 2016: Biomedical Applications in Molecular, Structural, and Functional Imaging, 97882J (29 March 2016); doi: 10.1117/12.2216491
Show Author Affiliations
Prahlad G. Menon, Duquesne Univ. (United States)
Univ. of Pittsburgh (United States)
SYSU-CMU Joint Institute of Engineering (China)
Sotiris Nedios, Heart Ctr., Univ. Leipzig (Germany)
Gerhard Hindricks, Heart Ctr., Univ. Leipzig (Germany)
Andreas Bollmann, Heart Ctr., Univ. Leipzig (Germany)

Published in SPIE Proceedings Vol. 9788:
Medical Imaging 2016: Biomedical Applications in Molecular, Structural, and Functional Imaging
Barjor Gimi; Andrzej Krol, Editor(s)

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