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Proceedings Paper

A pilot DTI analysis in patients with recent onset post-traumatic stress disorder
Author(s): Yang Liu; Liang Li; Baojuan Li; Xi Zhang; Hongbing Lu
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Paper Abstract

To explore the alteration in white matter between survivors with recent onset post-traumatic stress disorder (PTSD) and without PTSD, who survived from the same coal mine flood disaster, the diffusion tensor imaging (DTI) sequences were analyzed using DTI studio and statistical parametric mapping (SPM) packages in this paper. From DTI sequence, the fractional anisotropy (FA) value describes the degree of anisotropy of a diffusion process, while the apparent diffusion coefficient (ADC) value reflects the magnitude of water diffusion. The DTI analyses between PTSD and non-PTSD indicate lower FA values in the right caudate nucleus, right middle temporal gyrus, right fusiform gyrus, and right superior temporal gyrus, and higher ADC values in the right superior temporal gyrus and right corpus callosum of the subjects with PTSD. These results are partly in line with our previous volume and cortical thickness analyses, indicating the importance of multi-modality analysis for PTSD.

Paper Details

Date Published: 29 March 2016
PDF: 7 pages
Proc. SPIE 9788, Medical Imaging 2016: Biomedical Applications in Molecular, Structural, and Functional Imaging, 97881E (29 March 2016); doi: 10.1117/12.2216389
Show Author Affiliations
Yang Liu, Fourth Military Medical Univ. (China)
Liang Li, Fourth Military Medical Univ. (China)
Baojuan Li, Fourth Military Medical Univ. (China)
Xi Zhang, Fourth Military Medical Univ. (China)
Hongbing Lu, Fourth Military Medical Univ. (China)


Published in SPIE Proceedings Vol. 9788:
Medical Imaging 2016: Biomedical Applications in Molecular, Structural, and Functional Imaging
Barjor Gimi; Andrzej Krol, Editor(s)

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