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Proceedings Paper

An MRI guided system for prostate laser ablation with treatment planning and multi-planar temperature monitoring
Author(s): Sheng Xu; Harsh Agarwal; Marcelino Bernardo; Reza Seifabadi; Baris Turkbey; Ari Partanen; Ayele Negussie; Neil Glossop; Peter Choyke; Peter Pinto; Bradford J. Wood
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Paper Abstract

Prostate cancer is often over treated with standard treatment options which impact the patients’ quality of life. Laser ablation has emerged as a new approach to treat prostate cancer while sparing the healthy tissue around the tumor. Since laser ablation has a small treatment zone with high temperature, it is necessary to use accurate image guidance and treatment planning to enable full ablation of the tumor. Intraoperative temperature monitoring is also desirable to protect critical structures from being damaged in laser ablation. In response to these problems, we developed a navigation platform and integrated it with a clinical MRI scanner and a side firing laser ablation device. The system allows imaging, image guidance, treatment planning and temperature monitoring to be carried out on the same platform. Temperature sensing phantoms were developed to demonstrate the concept of iterative treatment planning and intraoperative temperature monitoring. Retrospective patient studies were also conducted to show the clinical feasibility of the system.

Paper Details

Date Published: 18 March 2016
PDF: 7 pages
Proc. SPIE 9786, Medical Imaging 2016: Image-Guided Procedures, Robotic Interventions, and Modeling, 97861I (18 March 2016); doi: 10.1117/12.2216084
Show Author Affiliations
Sheng Xu, National Institutes of Health (United States)
Harsh Agarwal, Philips Research North America (United States)
Marcelino Bernardo, National Institutes of Health (United States)
Reza Seifabadi, National Institutes of Health (United States)
Baris Turkbey, National Institutes of Health (United States)
Ari Partanen, Philips Healthcare (United States)
Ayele Negussie, National Institutes of Health (United States)
Neil Glossop, ArciTrax Inc. (Canada)
Peter Choyke, National Institutes of Health (United States)
Peter Pinto, National Institutes of Health (United States)
Bradford J. Wood, National Institutes of Health (United States)


Published in SPIE Proceedings Vol. 9786:
Medical Imaging 2016: Image-Guided Procedures, Robotic Interventions, and Modeling
Robert J. Webster; Ziv R. Yaniv, Editor(s)

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