Share Email Print
cover

Proceedings Paper

In-vivo cutaneous burn characterization and scar assay with multi-functional optical coherence tomography (Conference Presentation)
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

Research about the cutaneous burn was separated by assessment of burn depth and development of wound healing therapy. Various in vivo optical techniques were used to determined burn depth and observe the wound healing process. In this paper, we report the usage of multimodal optical coherence tomography system, which containing angiographic and polarization sensitive OCT (PS-OCT) with conventional OCT system, at burn studies. Burn was induced at 4 different degrees by control the attachment time of 75 Celsius degree heated brass rod at dorsal skin of the rat. For the burn depth assessment, we imaged the different burn degrees area. Changes of polarization sensitive signal were providing burn depth information. To see the wound healing process, each wound area imaged at long period. Conventional OCT shows the structural information about the tissue, like layer and hair follicle. Angiographic OCT provides vascular distribution and diameter of blood vessel information and PS-OCT shows birefringence tissue information. Based on the multimodal OCT data, burn depth assessment were well matched with burn induced time and wound healing process was consistent with previous wound healing report. Therefore, the multimodal OCT holds potential for burn study.

Paper Details

Date Published: 26 April 2016
PDF: 1 pages
Proc. SPIE 9697, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XX, 96971C (26 April 2016); doi: 10.1117/12.2214817
Show Author Affiliations
Bumju Kim, Pohang Univ. of Science and Technology (Korea, Republic of)
Yeorum Yoon, Pohang Univ. of Science and Technology (Korea, Republic of)
Viet-Hoan Le, Pohang Univ. of Science and Technology (Korea, Republic of)
Calvin J. Yoon, Pohang Univ. of Science and Technology (Korea, Republic of)
Ki Hean Kim, Pohang Univ. of Science and Technology (Korea, Republic of)


Published in SPIE Proceedings Vol. 9697:
Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XX
Joseph A. Izatt; James G. Fujimoto; Valery V. Tuchin, Editor(s)

© SPIE. Terms of Use
Back to Top