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Proceedings Paper

Angiographic imaging using an 18.9 MHz swept-wavelength laser that is phase-locked to the data acquisition clock and resonant scanners (Conference Presentation)
Author(s): Serhat Tozburun; Cedric Blatter; Meena Siddiqui; Ahhyun S Nam; Benjamin J Vakoc
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Paper Abstract

In this study, we present an angiographic system comprised from a novel 18.9 MHz swept wavelength source integrated with a MEMs-based 23.7 kHz fast-axis scanner. The system provides rapid acquisition of frames and volumes on which a range of Doppler and intensity-based angiographic analyses can be performed. Interestingly, the source and data acquisition computer can be directly phase-locked to provide an intrinsically phase stable imaging system supporting Doppler measurements without the need for individual A-line triggers or post-processing phase calibration algorithms. The system is integrated with a 1.8 Gigasample (GS) per second acquisition card supporting continuous acquisition to computer RAM for 10 seconds. Using this system, we demonstrate phase-stable acquisitions across volumes acquired at 60 Hz frequency. We also highlight the ability to perform c-mode angiography providing volume perfusion measurements with 30 Hz temporal resolution. Ultimately, the speed and phase-stability of this laser and MEMs scanner platform can be leveraged to accelerate OCT-based angiography and both phase-sensitive and phase-insensitive extraction of blood flow velocity.

Paper Details

Date Published: 26 April 2016
PDF: 1 pages
Proc. SPIE 9697, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XX, 969708 (26 April 2016); doi: 10.1117/12.2214775
Show Author Affiliations
Serhat Tozburun, Wellman Ctr. for Photomedicine (United States)
Cedric Blatter, Wellman Ctr. for Photomedicine (United States)
Meena Siddiqui, Wellman Ctr. for Photomedicine, Massachusetts General Hospital (United States)
Ahhyun S Nam, Massachusetts Institute of Technology (United States)
Benjamin J Vakoc, Wellman Ctr for Photomedicine (United States)


Published in SPIE Proceedings Vol. 9697:
Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XX
Joseph A. Izatt; James G. Fujimoto; Valery V. Tuchin, Editor(s)

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