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Proceedings Paper

Label-free pathological evaluation of grade 3 cancer using Stokes shift spectroscopy
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Paper Abstract

In this study, Stokes shift spectroscopy (S3) is used for measuring the aggressiveness of malignant tumors. S3 is an optical tool which utilizes the difference between the emission wavelength (λem) and the absorption wavelength (λabs) (the Stokes shift) to give a fixed wavelength shift (Δλs).Our analysis of tumor samples using S3 shows grade 3 (high grade) cancers consistently have increased relative tryptophan content compared to grade 1 or 2 tumors. This technique may be a useful tool in the evaluation of a patient’s cancer.

Paper Details

Date Published: 11 March 2016
PDF: 5 pages
Proc. SPIE 9703, Optical Biopsy XIV: Toward Real-Time Spectroscopic Imaging and Diagnosis, 97030W (11 March 2016); doi: 10.1117/12.2214327
Show Author Affiliations
Laura A. Sordillo, The City College of New York (United States)
Peter P. Sordillo, The City College of New York (United States)
R. R. Alfano, The City College of New York (United States)


Published in SPIE Proceedings Vol. 9703:
Optical Biopsy XIV: Toward Real-Time Spectroscopic Imaging and Diagnosis
Robert R. Alfano; Stavros G. Demos, Editor(s)

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