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Proceedings Paper

Imaging vascular dynamics in human retina using full-field swept-source optical coherence tomography (Conference Presentation)
Author(s): Hendrik Spahr; Dierck Hillmann; Carola Hain; Clara Pfäffle; Helge Sudkamp; Gesa Franke; Gereon Hüttmann
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Paper Abstract

We demonstrate a new non-invasive method to assess the functional condition of the retinal vascular system. Phase-sensitive full-field swept-source optical coherence tomography (PhS-FF-SS-OCT) is used to investigate retinal vascular dynamics at unprecedented temporal resolution. Motion of retinal tissue, that is induced by expansion of the vessels therein, is measured with an accuracy of about 10 nm. The pulse shape of arterial and venous pulsation, their temporal delay as well as the frequency dependent pulse propagation through the capillary bed are determined. For the first time, imaging speed and motion sensitivity are sufficient for a direct measurement of pulse waves propagating with more than 600 mm/s in retinal vessels of a healthy young subject.

Paper Details

Date Published: 26 April 2016
PDF: 1 pages
Proc. SPIE 9697, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XX, 96970E (26 April 2016); doi: 10.1117/12.2214303
Show Author Affiliations
Hendrik Spahr, Univ. zu Lübeck (Germany)
Medizinisches Laserzentrum Lübeck GmbH (Germany)
Dierck Hillmann, Thorlabs GmbH (Germany)
Carola Hain, Univ. zu Lübeck (Germany)
Medizinisches Laserzentrum Lübeck GmbH (Germany)
Clara Pfäffle, Univ. zu Lübeck (Germany)
Medizinisches Laserzentrum Lübeck GmbH (Germany)
Helge Sudkamp, Univ. zu Lübeck (Germany)
Medizinisches Laserzentrum Lübeck GmbH (Germany)
Gesa Franke, Univ. zu Lübeck (Germany)
Medizinisches Laserzentrum Lübeck GmbH (Germany)
Gereon Hüttmann, Univ. zu Lübeck (Germany)
Medizinisches Laserzentrum Lübeck GmbH (Germany)


Published in SPIE Proceedings Vol. 9697:
Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XX
Joseph A. Izatt; James G. Fujimoto; Valery V. Tuchin, Editor(s)

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