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Proceedings Paper

Fluorescence-guided tumor visualization using a custom designed NIR attachment to a surgical microscope for high sensitivity imaging (Conference Presentation)
Author(s): David S. Kittle; Chirag G. Patil; Adam Mamelak; Stacey Hansen; Jeff Perry; Laura Ishak; Keith L. Black; Pramod V. Butte

Paper Abstract

Current surgical microscopes are limited in sensitivity for NIR fluorescence. Recent developments in tumor markers attached with NIR dyes require newer, more sensitive imaging systems with high resolution to guide surgical resection. We report on a small, single camera solution enabling advanced image processing opportunities previously unavailable for ultra-high sensitivity imaging of these agents. The system captures both visible reflectance and NIR fluorescence at 300 fps while displaying full HD resolution video at 60 fps. The camera head has been designed to easily mount onto the Zeiss Pentero microscope head for seamless integration into surgical procedures.

Paper Details

Date Published: 26 April 2016
PDF: 1 pages
Proc. SPIE 9690, Clinical and Translational Neurophotonics; Neural Imaging and Sensing; and Optogenetics and Optical Manipulation, 96900I (26 April 2016); doi: 10.1117/12.2214278
Show Author Affiliations
David S. Kittle, Cedars-Sinai Medical Ctr. (United States)
Chirag G. Patil, Cedars-Sinai Medical Ctr. (United States)
Adam Mamelak, Cedars-Sinai Medical Ctr. (United States)
Stacey Hansen, Blaze Bioscience, Inc. (United States)
Jeff Perry, Blaze Bioscience, Inc. (United States)
Laura Ishak, Blaze Bioscience, Inc. (United States)
Keith L. Black, Cedars-Sinai Medical Ctr. (United States)
Pramod V. Butte, Cedars-Sinai Medical Ctr. (United States)


Published in SPIE Proceedings Vol. 9690:
Clinical and Translational Neurophotonics; Neural Imaging and Sensing; and Optogenetics and Optical Manipulation
Steen J. Madsen; E. Duco Jansen; Samarendra K. Mohanty; Nitish V. Thakor; Qingming Luo; Victor X. D. Yang, Editor(s)

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