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Proceedings Paper

SERS sensing of sub-nanoliter analyte on diatom biosilica using inkjet printing
Author(s): Yuting Xi; Xianming Kong; Kenny Squire; Paul LeDuff; Gregory L. Rorrer; Alan X. Wang
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Paper Abstract

Diatoms are unicellular algae which have photonic-crystal-like biosilica frustules consisting of many pores. Each diatom frustule has a dimension around 10~20μm and can be used as a miniaturized biosensor. In this article, we demonstrate surface-enhanced Raman scattering (SERS) sensing of sub-nanoliter analyte on diatom biosilica with self-assembled silver nanoparticles (Ag NPs). An inkjet printer is used to dispense multiple ~100 pico-liter volume analyte droplets with pinpoint accuracy and precision onto each individual diatom frustule. Experimental results show up to 3x higher SERS signals of R6G on diatom compared with those from conventional colloidal SERS substrates. Furthermore, down to 10-14M R6G detection ability was also demonstrated through the inkjet printing strategy.

Paper Details

Date Published: 22 April 2016
PDF: 6 pages
Proc. SPIE 9724, Plasmonics in Biology and Medicine XIII, 972406 (22 April 2016); doi: 10.1117/12.2214005
Show Author Affiliations
Yuting Xi, Oregon State Univ. (United States)
Xianming Kong, Oregon State Univ. (United States)
Kenny Squire, Oregon State Univ. (United States)
Paul LeDuff, Oregon State Univ. (United States)
Gregory L. Rorrer, Oregon State Univ. (United States)
Alan X. Wang, Oregon State Univ. (United States)

Published in SPIE Proceedings Vol. 9724:
Plasmonics in Biology and Medicine XIII
Tuan Vo-Dinh; Joseph R. Lakowicz, Editor(s)

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