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Proceedings Paper

All-optical pulse-echo ultrasound probe for intravascular imaging (Conference Presentation)
Author(s): Richard J. Colchester; Sacha Noimark; Charles A. Mosse; Edward Z. Zhang; Paul C. Beard; Ivan P Parkin; Ioannis Papakonstantinou; Adrien E. Desjardins

Paper Abstract

High frequency ultrasound probes such as intravascular ultrasound (IVUS) and intracardiac echocardiography (ICE) catheters can be invaluable for guiding minimally invasive medical procedures in cardiology such as coronary stent placement and ablation. With current-generation ultrasound probes, ultrasound is generated and received electrically. The complexities involved with fabricating these electrical probes can result in high costs that limit their clinical applicability. Additionally, it can be challenging to achieve wide transmission bandwidths and adequate wideband reception sensitivity with small piezoelectric elements. Optical methods for transmitting and receiving ultrasound are emerging as alternatives to their electrical counterparts. They offer several distinguishing advantages, including the potential to generate and detect the broadband ultrasound fields (tens of MHz) required for high resolution imaging. In this study, we developed a miniature, side-looking, pulse-echo ultrasound probe for intravascular imaging, with fibre-optic transmission and reception. The axial resolution was better than 70 microns, and the imaging depth in tissue was greater than 1 cm. Ultrasound transmission was performed by photoacoustic excitation of a carbon nanotube/polydimethylsiloxane composite material; ultrasound reception, with a fibre-optic Fabry-Perot cavity. Ex vivo tissue studies, which included healthy swine tissue and diseased human tissue, demonstrated the strong potential of this technique. To our knowledge, this is the first study to achieve an all-optical pulse-echo ultrasound probe for intravascular imaging. The potential for performing all-optical B-mode imaging (2D and 3D) with virtual arrays of transmit/receive elements, and hybrid imaging with pulse-echo ultrasound and photoacoustic sensing are discussed.

Paper Details

Date Published: 27 April 2016
PDF: 1 pages
Proc. SPIE 9689, Photonic Therapeutics and Diagnostics XII, 96893I (27 April 2016); doi: 10.1117/12.2213757
Show Author Affiliations
Richard J. Colchester, Univ. College London (United Kingdom)
Sacha Noimark, University (United Kingdom)
Univ. College London (United Kingdom)
Charles A. Mosse, Univ. College London (United Kingdom)
Edward Z. Zhang, Univ. College London (United Kingdom)
Paul C. Beard, Univ. College London (United Kingdom)
Ivan P Parkin, University College London (United Kingdom)
Ioannis Papakonstantinou, Univ. College London (United Kingdom)
Adrien E. Desjardins, Univ. College London (United Kingdom)

Published in SPIE Proceedings Vol. 9689:
Photonic Therapeutics and Diagnostics XII
Hyun Wook Kang; Guillermo J. Tearney; Melissa C. Skala; Bernard Choi; Andreas Mandelis; Brian J. F. Wong; Justus F. Ilgner; Nikiforos Kollias; Paul J. Campagnola; Kenton W. Gregory; Laura Marcu; Haishan Zeng, Editor(s)

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