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Proceedings Paper

Methods for effective fluorophore injection and imaging of lymphatics in small animals
Author(s): Alisha V. DSouza; Kayla A. Marra; Jason R. Gunn; Kimberley S. Samkoe; Kenneth M. Tichauer; Brian W. Pogue
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Paper Abstract

Morbidity and complexity involved in lymph node staging via surgical resection and biopsy calls for staging techniques that are less invasive. While visible blue dyes are commonly used in locating sentinel lymph nodes, since they follow tumor-draining lymphatic vessels, they do not provide a metric to evaluate presence of cancer. An area of active research is to use fluorescent dyes to assess tumor burden of sentinel and secondary lymph nodes. The goal of this work was to successfully perform fluorescence imaging of IRDye®680RD in the lymphatics, in a repeatable manner.

Paper Details

Date Published: 4 March 2016
PDF: 4 pages
Proc. SPIE 9696, Molecular-Guided Surgery: Molecules, Devices, and Applications II, 96960W (4 March 2016); doi: 10.1117/12.2213675
Show Author Affiliations
Alisha V. DSouza, Thayer School of Engineering at Dartmouth (United States)
Kayla A. Marra, Thayer School of Engineering at Dartmouth (United States)
Jason R. Gunn, Thayer School of Engineering at Dartmouth (United States)
Kimberley S. Samkoe, Thayer School of Engineering at Dartmouth (United States)
Geisel School of Medicine (United States)
Kenneth M. Tichauer, Illinois Institute of Technology (United States)
Brian W. Pogue, Thayer School of Engineering at Dartmouth (United States)
Geisel School of Medicine (United States)


Published in SPIE Proceedings Vol. 9696:
Molecular-Guided Surgery: Molecules, Devices, and Applications II
Brian W. Pogue; Sylvain Gioux, Editor(s)

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