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Proceedings Paper

Design of an everting balloon to deploy a microendoscope to the fallopian tubes
Author(s): Molly Keenan; Caitlin Howard; Tyler Tate; Ian McGuiness; Alexis Sauer-Budge; John Black; Urs Utzinger; Jennifer K. Barton
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Paper Abstract

The 5-year survival rate for ovarian cancer is only 45% largely due to lack of effective screening methods. Current methods include palpation, transvaginal ultrasound, and the CA-125 blood test. Finding disease reliably and at an early stage increase survival to 92%. We have designed and built a 0.7 mm endoscope for the early detection of ovarian cancer. Inserted transvaginally through the working channel of a hysteroscope, the falloposcope creates a minimally invasive procedure for the screening of high risk women. To improve the ease-of-use and safety of falloposcope deployment, we are working to create an everting balloon. Currently, the falloposcope would require a skilled user to operate due to the challenging anatomy of the fallopian tubes – a small opening from the uterus (< 1 mm), tortuous path, and delicate lumenal features. A balloon delivery system would gently open the fallopian tube and guide the falloposcope down the center of lumen. We show balloon design and discuss integration with the falloposcope prototype. We test possible mechanical damage to the tissue due to scraping, puncture, or overstretching. Successful introduction of the everting balloon to simplify falloposcope delivery could expand screening beyond specialized centers to smaller clinical locations.

Paper Details

Date Published: 8 March 2016
PDF: 6 pages
Proc. SPIE 9689, Photonic Therapeutics and Diagnostics XII, 968944 (8 March 2016); doi: 10.1117/12.2213345
Show Author Affiliations
Molly Keenan, The Univ. of Arizona (United States)
Caitlin Howard, The Univ. of Arizona (United States)
Tyler Tate, College of Optical Sciences, Univ. of Arizona (United States)
Ian McGuiness, Fraunhofer USA, Inc. (United States)
Alexis Sauer-Budge, Fraunhofer USA, Inc. (United States)
Boston Univ. (United States)
John Black, Glannaventa, Inc. (United States)
Urs Utzinger, The Univ. of Arizona (United States)
College of Optical Sciences, Univ. of Arizona (United States)
Jennifer K. Barton, Univ of Arizona (United States)
College of Optical Sciences, Univ. of Arizona (United States)


Published in SPIE Proceedings Vol. 9689:
Photonic Therapeutics and Diagnostics XII
Hyun Wook Kang; Guillermo J. Tearney; Melissa C. Skala; Bernard Choi; Andreas Mandelis; Brian J. F. Wong; Justus F. Ilgner; Nikiforos Kollias; Paul J. Campagnola; Kenton W. Gregory; Laura Marcu; Haishan Zeng, Editor(s)

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