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Proceedings Paper

Optical coherence tomography imaging to analyze biofilm thickness from distal to proximal regions of the endotracheal tubes
Author(s): Robert E. Dunn; Andrew E. Heidari; Samer Moghaddam; Mengke Zhang; Changhoon Han; Kyung-Jin Oh; Steve Leven; Matthew Brenner; Carl Genberg; Zhongping Chen
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Paper Abstract

The development of nosocomial ventilator-associated pneumonia (VAP) has been linked to the presence of specific bacteria found in the biofilm that develops in intubated endotracheal tubes of critical care patients. Presence of biofilm has been difficult to assess clinically. Here, we use Optical coherence tomography (OCT), to visualize the biofilm at both the proximal and distal tips. Ultimately, the goal will be to determine if OCT can be a tool to visualize biofilm development and potential interventions to reduce the incidence of VAP.

Paper Details

Date Published: 8 March 2016
PDF: 7 pages
Proc. SPIE 9691, Endoscopic Microscopy XI; and Optical Techniques in Pulmonary Medicine III, 96911G (8 March 2016); doi: 10.1117/12.2213247
Show Author Affiliations
Robert E. Dunn, Univ. of California, Irvine (United States)
Beckman Laser Institute (United States)
Andrew E. Heidari, Univ. of California, Irvine (United States)
Beckman Laser Institute (United States)
Samer Moghaddam, Univ. of California, Irvine Medical Ctr. (United States)
Mengke Zhang, Beckman Laser Institute (United States)
Changhoon Han, Chonnam National Univ. Medical School (Korea, Republic of)
Kyung-Jin Oh, Chonnam National Univ. Medical School (Korea, Republic of)
Steve Leven, Univ. of California, Irvine Medical Ctr. (United States)
Matthew Brenner, Univ. of California, Irvine Medical Ctr. (United States)
Beckman Laser Institute (United States)
Carl Genberg, N8 Medical, Inc. (United States)
Zhongping Chen, Univ. of California, Irvine (United States)


Published in SPIE Proceedings Vol. 9691:
Endoscopic Microscopy XI; and Optical Techniques in Pulmonary Medicine III
Melissa J. Suter; Guillermo J. Tearney; Thomas D. Wang; Stephen Lam; Matthew Brenner, Editor(s)

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