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Proceedings Paper

Towards multimodal detection of melanoma thickness based on optical coherence tomography and optoacoustics
Author(s): M. Rahlves; A. Varkentin; J. Stritzel; E. Blumenröther; M. Mazurenka; M. Wollweber; B. Roth
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Paper Abstract

Melanoma skin cancer has one of the highest mortality rates of all types of cancer if not detected at an early stage. The survival rate is highly dependent on its penetration depth, which is commonly determined by histopathology. In this work, we aim at combining optical coherence tomography and optoacoustic as a non-invasive all-optical method to measure the penetration depth of melanoma. We present our recent achievements to setup a handheld multimodal device and also results from first in vivo measurements on healthy and cancerous skin tissue, which are compared to measurements obtained by ultrasound and histopathology.

Paper Details

Date Published: 7 March 2016
PDF: 6 pages
Proc. SPIE 9701, Multimodal Biomedical Imaging XI, 97010F (7 March 2016); doi: 10.1117/12.2213132
Show Author Affiliations
M. Rahlves, Leibniz Univ. Hannover (Germany)
A. Varkentin, Leibniz Univ. Hannover (Germany)
J. Stritzel, Leibniz Univ. Hannover (Germany)
E. Blumenröther, Leibniz Univ. Hannover (Germany)
M. Mazurenka, Leibniz Univ. Hannover (Germany)
M. Wollweber, Leibniz Univ. Hannover (Germany)
B. Roth, Leibniz Univ. Hannover (Germany)

Published in SPIE Proceedings Vol. 9701:
Multimodal Biomedical Imaging XI
Fred S. Azar; Xavier Intes, Editor(s)

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