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Proceedings Paper

The blood perfusion and NADH/FAD content combined analysis in patients with diabetes foot
Author(s): Victor V. Dremin; Victor V. Sidorov; Alexander I. Krupatkin; Gagik R. Galstyan; Irina N. Novikova; Angelina I. Zherebtsova; Evgeny A. Zherebtsov; Andrey V. Dunaev; Zera N. Abdulvapova; Karina S. Litvinova; Ilya E. Rafailov; Sergei G. Sokolovski; Edik U. Rafailov
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Paper Abstract

Skin blood microcirculation and the metabolism activity of tissue were examined on the patients with type 2 diabetes. Laser Doppler flowmetry (LDF) with 1064 nm laser light source and fluorescence spectroscopy (FS) with excitation light of 365 nm and 450 nm have been used to monitor the blood perfusion and the content of coenzymes NADH and FAD. Concluding, the proposed combined LDF and tissue FS approach allows to identify the significant violations in the blood microcirculation and metabolic activity for type 2 diabetes patients.

Paper Details

Date Published: 7 March 2016
PDF: 7 pages
Proc. SPIE 9698, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIV, 969810 (7 March 2016); doi: 10.1117/12.2212758
Show Author Affiliations
Victor V. Dremin, State Univ. Education-Science-Production Complex (Russian Federation)
Victor V. Sidorov, SPE LAZMA Ltd. (Russian Federation)
Alexander I. Krupatkin, Priorov Central Research Institute of Traumatology and Orthopedics (Russian Federation)
Gagik R. Galstyan, Endocrinology Research Ctr. of the Ministry of Health (Russian Federation)
Irina N. Novikova, State Univ. Education-Science-Production Complex (Russian Federation)
Angelina I. Zherebtsova, State Univ. Education-Science-Production Complex (Russian Federation)
Evgeny A. Zherebtsov, State Univ. Education-Science-Production Complex (Russian Federation)
Andrey V. Dunaev, State Univ. Education-Science-Production Complex (Russian Federation)
Zera N. Abdulvapova, Endocrinology Research Ctr. of the Ministry of Health (Russian Federation)
Karina S. Litvinova, Aston Univ. (United Kingdom)
Ilya E. Rafailov, Aston Univ. (United Kingdom)
Sergei G. Sokolovski, Aston Univ. (United Kingdom)
Edik U. Rafailov, Aston Univ. (United Kingdom)


Published in SPIE Proceedings Vol. 9698:
Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIV
Tuan Vo-Dinh; Anita Mahadevan-Jansen; Warren S. Grundfest, Editor(s)

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