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Proceedings Paper

Steady state fluorescence spectroscopic characterization of normal and diabetic urine at selective excitation wavelength 280 nm
Author(s): Anjana Kesavan; Rekha Pachaiappan; Prakasa Rao Aruna; Singaravelu Ganesan
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Paper Abstract

Urine is considered diagnostically important for tits native fluorophores and they vary in their distribution, concentration and physiochemical properties, depending upon the metabolic condition of the subject. In this study, we have made an attempt, to characterize the urine of normal subject and diabetic patients under medication by native fluorescence spectroscopy at 280 nm excitation. Further, the fluorescence data were analyzed employing the multivariate statistical method linear discriminant analysis (LDA) using leave one out cross validation method. The results were promising in discriminating diabetic urine from that of normal urine. This study in future may be extended to check the feasibility in ruling out the coexisting disorders such as cancer.

Paper Details

Date Published: 7 March 2016
PDF: 4 pages
Proc. SPIE 9703, Optical Biopsy XIV: Toward Real-Time Spectroscopic Imaging and Diagnosis, 97031H (7 March 2016); doi: 10.1117/12.2212625
Show Author Affiliations
Anjana Kesavan, Anna Univ., Chennai (India)
Rekha Pachaiappan, Anna Univ., Chennai (India)
Prakasa Rao Aruna, Anna Univ., Chennai (India)
Singaravelu Ganesan, Anna Univ., Chennai (India)

Published in SPIE Proceedings Vol. 9703:
Optical Biopsy XIV: Toward Real-Time Spectroscopic Imaging and Diagnosis
Robert R. Alfano; Stavros G. Demos, Editor(s)

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