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Proceedings Paper

Raman and surface-enhanced Raman spectroscopy for renal condition monitoring
Author(s): Jingting Li; Ming Li; Yong Du; Greggy M. Santos; Chandra Mohan; Wei-Chuan Shih
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Paper Abstract

Non- and minimally-invasive techniques can provide advantages in the monitoring and clinical diagnostics in renal diseases. Although renal biopsy may be useful in establishing diagnosis in several diseases, it is an invasive approach and impractical for longitudinal disease monitoring. To address this unmet need, we have developed two techniques based on Raman spectroscopy. First, we have investigated the potential of diagnosing and staging nephritis by analyzing kidney tissue Raman spectra using multivariate techniques. Secondly, we have developed a urine creatinine sensor based on surface-enhanced Raman spectroscopy with performance near commercial assays which require relatively laborious sample preparation and longer time.

Paper Details

Date Published: 7 March 2016
PDF: 9 pages
Proc. SPIE 9704, Biomedical Vibrational Spectroscopy 2016: Advances in Research and Industry, 97040T (7 March 2016); doi: 10.1117/12.2212573
Show Author Affiliations
Jingting Li, Univ. of Houston (United States)
Ming Li, Univ. of Houston (United States)
Yong Du, Univ. of Houston (United States)
Greggy M. Santos, Univ. of Houston (United States)
Chandra Mohan, Univ. of Houston (United States)
Wei-Chuan Shih, Univ. of Houston (United States)


Published in SPIE Proceedings Vol. 9704:
Biomedical Vibrational Spectroscopy 2016: Advances in Research and Industry
Anita Mahadevan-Jansen; Wolfgang Petrich, Editor(s)

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