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Proceedings Paper

Optical characterization of tissue mimicking phantoms by a vertical double integrating sphere system
Author(s): Yilin Han; Qiumin Jia; Shuwei Shen; Guangli Liu; Yuwei Guo; Ximing Zhou; Jiaru Chu; Gang Zhao; Erbao Dong; David W. Allen; Paul Lemaillet; Ronald Xu
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Paper Abstract

Accurate characterization of absorption and scattering properties for biologic tissue and tissue-simulating materials enables 3D printing of traceable tissue-simulating phantoms for medical spectral device calibration and standardized medical optical imaging. Conventional double integrating sphere systems have several limitations and are suboptimal for optical characterization of liquid and soft materials used in 3D printing. We propose a vertical double integrating sphere system and the associated reconstruction algorithms for optical characterization of phantom materials that simulate different human tissue components. The system characterizes absorption and scattering properties of liquid and solid phantom materials in an operating wavelength range from 400 nm to 1100 nm. Absorption and scattering properties of the phantoms are adjusted by adding titanium dioxide powder and India ink, respectively. Different material compositions are added in the phantoms and characterized by the vertical double integrating sphere system in order to simulate the human tissue properties. Our test results suggest that the vertical integrating sphere system is able to characterize optical properties of tissue-simulating phantoms without precipitation effect of the liquid samples or wrinkling effect of the soft phantoms during the optical measurement.

Paper Details

Date Published: 18 March 2016
PDF: 11 pages
Proc. SPIE 9700, Design and Quality for Biomedical Technologies IX, 97000A (18 March 2016); doi: 10.1117/12.2212287
Show Author Affiliations
Yilin Han, Univ. of Science and Technology of China (China)
Qiumin Jia, Univ. of Science and Technology of China (China)
Shuwei Shen, Univ. of Science and Technology of China (China)
Guangli Liu, Univ. of Science and Technology of China (China)
Yuwei Guo, Univ. of Science and Technology of China (China)
Ximing Zhou, Univ. of Science and Technology of China (China)
Jiaru Chu, Univ. of Science and Technology of China (China)
Gang Zhao, Univ. of Science and Technology of China (China)
Erbao Dong, Univ. of Science and Technology of China (China)
David W. Allen, National Institute of Standards and Technology (United States)
Paul Lemaillet, National Institute of Standards and Technology (United States)
Ronald Xu, Univ. of Science and Technology of China (China)
The Ohio State Univ. (United States)


Published in SPIE Proceedings Vol. 9700:
Design and Quality for Biomedical Technologies IX
Ramesh Raghavachari; Rongguang Liang, Editor(s)

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