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Proceedings Paper

New insights into photodynamic therapy treatment through the use of 3D Monte Carlo radiation transfer modelling
Author(s): C. Louis Campbell; Kenneth Wood; C. Tom A. Brown; Harry Moseley
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Paper Abstract

Photodynamic therapy (PDT) has been theoretically investigated using a Monte Carlo radiation transfer (MCRT) model. By including complex three dimensional (3D) tumour models a more appropriate representation of the treatment was achieved. The 3D clustered tumour model was compared to a smooth model, resulting in a significantly deeper penetration associated with the clustered model. The results from the work presented here indicates that light might penetrate deeper than suggested by 2D or simple layered models.

Paper Details

Date Published: 29 February 2016
PDF: 10 pages
Proc. SPIE 9689, Photonic Therapeutics and Diagnostics XII, 96890Q (29 February 2016); doi: 10.1117/12.2212240
Show Author Affiliations
C. Louis Campbell, Univ. of St. Andrews (United Kingdom)
Kenneth Wood, Univ. of St. Andrews (United Kingdom)
C. Tom A. Brown, Univ. of St. Andrews (United Kingdom)
Harry Moseley, Univ. of Dundee (United Kingdom)

Published in SPIE Proceedings Vol. 9689:
Photonic Therapeutics and Diagnostics XII
Hyun Wook Kang; Guillermo J. Tearney M.D.; Melissa C. Skala; Bernard Choi; Andreas Mandelis; Brian J. F. Wong M.D.; Justus F. Ilgner M.D.; Nikiforos Kollias; Paul J. Campagnola; Kenton W. Gregory M.D.; Laura Marcu; Haishan Zeng, Editor(s)

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