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Proceedings Paper

Volumetric imaging of fast biological dynamics in deep tissue via wavefront engineering
Author(s): Lingjie Kong; Jianyong Tang; Meng Cui
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Paper Abstract

To reveal fast biological dynamics in deep tissue, we combine two wavefront engineering methods that were developed in our laboratory, namely optical phase-locked ultrasound lens (OPLUL) based volumetric imaging and iterative multiphoton adaptive compensation technique (IMPACT). OPLUL is used to generate oscillating defocusing wavefront for fast axial scanning, and IMPACT is used to compensate the wavefront distortions for deep tissue imaging. We show its promising applications in neuroscience and immunology.

Paper Details

Date Published: 15 March 2016
PDF: 7 pages
Proc. SPIE 9717, Adaptive Optics and Wavefront Control for Biological Systems II, 97170J (15 March 2016); doi: 10.1117/12.2211417
Show Author Affiliations
Lingjie Kong, Purdue Univ. (United States)
Jianyong Tang, National Institutes of Health (United States)
Meng Cui, Purdue Univ. (United States)


Published in SPIE Proceedings Vol. 9717:
Adaptive Optics and Wavefront Control for Biological Systems II
Thomas G. Bifano; Joel Kubby; Sylvain Gigan, Editor(s)

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