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Proceedings Paper

Effect of interstitial low level laser therapy on tibial defect
Author(s): Sangyeob Lee; Myungjin Ha; Donghyun Hwang; Sungkon Yu; Seulki Jang; Jihoon Park; Edalat Radfar; Hansung Kim; Byungjo Jung
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Paper Abstract

Tibial defect is very common musculoskeletal disorder which makes patient painful and uncomfortable. Many studies about bone regeneration tried to figure out fast bone healing on early phase. It is already known that low level laser therapy (LLLT) is very convenient and good for beginning of bone disorder. However, light scattering and absorption obstruct musculoskeletal therapy which need optimal photon energy delivery. This study has used an interstitial laser probe (ILP) to overcome the limitations of light penetration depth and scattering. Animals (mouse, C57BL/6) were divided into three groups: laser treated test group 1 (660 nm; power 10 mW; total energy 5 J) and test group 2 (660 nm; power 20 mW; total energy 10 J); and untreated control group. All animals were taken surgical operation to make tibial defect on right crest of tibia. The test groups were treated every 48 hours with ILP. Bone volume and X-ray attenuation coefficient were measured on 0, 14th and 28th day with u-CT after treatment and were used to evaluate effect of LLLT. Results show that bone volume of test groups has been improved more than control group. X-ray attenuation coefficients of each groups have slightly different. The results suggest that LLLT combined with ILP may affect on early phase of bone regeneration and may be used in various musculoskeletal disease in deep tissue layer.

Paper Details

Date Published: 8 March 2016
PDF: 4 pages
Proc. SPIE 9695, Mechanisms of Photobiomodulation Therapy XI, 96950D (8 March 2016); doi: 10.1117/12.2211371
Show Author Affiliations
Sangyeob Lee, Yonsei Univ. (Korea, Republic of)
Myungjin Ha, Yonsei Univ. (Korea, Republic of)
Donghyun Hwang, Yonsei Univ. (Korea, Republic of)
Sungkon Yu, Yonsei Univ. (Korea, Republic of)
Seulki Jang, Yonsei Univ. (Korea, Republic of)
Jihoon Park, Yonsei Univ. (Korea, Republic of)
Edalat Radfar, Yonsei Univ. (Korea, Republic of)
Hansung Kim, Yonsei Univ. (Korea, Republic of)
Byungjo Jung, Yonsei Univ. (Korea, Republic of)


Published in SPIE Proceedings Vol. 9695:
Mechanisms of Photobiomodulation Therapy XI
Michael R. Hamblin; James D. Carroll; Praveen Arany, Editor(s)

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