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Proceedings Paper

A closed-loop dual-modulation multi-spectral polarimeter for glucose monitoring
Author(s): Zhen fang Yu; Casey W. Pirnstill; Gerard L. Coté
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Paper Abstract

Optical polarimetry is a promising noninvasive means of assessing glucose concentration in the aqueous humor of the eye. One the major limiting factors is time-varying cornea birefringence due to motion artifact, which prevents the realization of this device. In this study, we simultaneously utilize laser intensity modulation and Faraday polarization rotation modulation for a real-time closed-loop multi-spectral polarimeter for glucose monitoring in vitro. In this report, a real-time closed-loop dual-modulation dual-spectral polarimeter was presented and in vitro glucose measurements were performed demonstrating the accuracy and repeatability of this polarimeter.

Paper Details

Date Published: 4 March 2016
PDF: 6 pages
Proc. SPIE 9715, Optical Diagnostics and Sensing XVI: Toward Point-of-Care Diagnostics, 97150U (4 March 2016); doi: 10.1117/12.2211114
Show Author Affiliations
Zhen fang Yu, Univ. of Electronic Science and Technology of China (China)
Texas A&M Univ. (United States)
Casey W. Pirnstill, Texas A&M Univ. (United States)
Wright-Patterson Air Force Base (United States)
Gerard L. Coté, Texas A&M Univ. (United States)

Published in SPIE Proceedings Vol. 9715:
Optical Diagnostics and Sensing XVI: Toward Point-of-Care Diagnostics
Gerard L. Coté, Editor(s)

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