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Proceedings Paper

Depth-dependent displacement sensitivity analysis and the influence of Doppler angle for quantitative assessment of mechanical properties using phase-sensitive spectral domain optical coherence tomography
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Paper Abstract

Optical coherence elastography (OCE) asesses the mechanical properties of samples by applying a mechanical stimulation and detecting the resulting sample displacement using optical coherence tomography (OCT). OCE methods which utilise the phase of the OCT signal offer the potential to detect displacements on the sub-nanometre scale. However, the displacement sensitivity achieveable is directly related to the signal-to-noise ratio and phase stability of the underlying OCT system. Furthermore, the estimation of Doppler angle is imperative in accurately measuring the sample displacement. This work evaluates the contributions of each of these parameters for quantitative assessment of mechanical properties using phase-sensitive spectral domain OCT.

Paper Details

Date Published: 9 March 2016
PDF: 6 pages
Proc. SPIE 9710, Optical Elastography and Tissue Biomechanics III, 97100N (9 March 2016); doi: 10.1117/12.2210964
Show Author Affiliations
Gillian Lynch, National Univ. of Ireland Galway (Ireland)
Hrebesh Subhash, Colgate-Palmolive Global Technology Ctr. (United States)
Sergey Alexandrov, National Univ. of Ireland Galway (Ireland)
Martin Leahy, National Univ. of Ireland Galway (Ireland)


Published in SPIE Proceedings Vol. 9710:
Optical Elastography and Tissue Biomechanics III
Kirill V. Larin; David D. Sampson, Editor(s)

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