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Proceedings Paper

Towards supercontinuum-driven hyperspectral microscopy in the mid-infrared
Author(s): I. D. Lindsay; S. Valle; J. Ward; G. Stevens; M. Farries; L. Huot; C. Brooks; P. M. Moselund; R. M. Vinella; M. Abdalla; D. de Gaspari; R. M. von Wurtemberg; S. Smuk; H. Martijn; J. Nallala; N. Stone; C. Barta; R. Hasal; U. Moller; O. Bang; S. Sujecki; A. Seddon
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Paper Abstract

The extension of supercontinuum (SC) sources into the mid-infrared, via the use of uoride and chalcogenide optical fibers, potentially offers the high radiance of a laser combined with spectral coverage far exceeding that of typical tunable lasers and comparable to traditional black-body emitters. Together with advances in mid-IR imaging detectors and novel tunable filter designs, such supercontinua hold considerable potential as sources of illumination for spectrally-resolved microscopy targeting applications such as rapid histological screening. The ability to rapidly and arbitrarily select particular wavelengths of interest from a broad emission spectrum, covering a wide range of biologically relevant targets, lends itself to image acquisition only at key relevant wavelengths leading to more manageable datasets. However, in addition to offering new imaging modalities, SC sources also present a range of challenges to successful integration with typical spectral microscopy instrumentation, including appropriate utilisation of their high spatial coherence. In this paper the application of SC sources to spectrally-resolved microscopy in the mid-IR is discussed and systems-integration considerations specific to these sources highlighted. Preliminary results in the 3-5μm region, obtained within the European FP7 project MINERVA, are also presented here.

Paper Details

Date Published: 7 March 2016
PDF: 9 pages
Proc. SPIE 9703, Optical Biopsy XIV: Toward Real-Time Spectroscopic Imaging and Diagnosis, 970304 (7 March 2016); doi: 10.1117/12.2210836
Show Author Affiliations
I. D. Lindsay, Gooch & Housego Ltd. (United Kingdom)
S. Valle, Gooch & Housego Ltd. (United Kingdom)
J. Ward, Gooch & Housego Ltd. (United Kingdom)
G. Stevens, Gooch & Housego Ltd. (United Kingdom)
M. Farries, Gooch & Housego Ltd. (United Kingdom)
L. Huot, NKT Photonics A/S (Denmark)
C. Brooks, NKT Photonics A/S (Denmark)
P. M. Moselund, NKT Photonics A/S (Denmark)
R. M. Vinella, Xenics NV (Belgium)
M. Abdalla, Xenics NV (Belgium)
D. de Gaspari, Xenics NV (Belgium)
R. M. von Wurtemberg, IR Nova AB (Sweden)
S. Smuk, IR Nova AB (Sweden)
H. Martijn, IR Nova AB (Sweden)
J. Nallala, Univ. of Exeter (United Kingdom)
N. Stone, Univ. of Exeter (United Kingdom)
C. Barta, BBT-Materials Processing, s.r.o. Ltd. (Czech Republic)
R. Hasal, BBT-Materials Processing, s.r.o. Ltd. (Czech Republic)
U. Moller, DTU Fotonik (Denmark)
O. Bang, DTU Fotonik (Denmark)
S. Sujecki, The Univ. of Nottingham (United Kingdom)
A. Seddon, The Univ. of Nottingham (United Kingdom)

Published in SPIE Proceedings Vol. 9703:
Optical Biopsy XIV: Toward Real-Time Spectroscopic Imaging and Diagnosis
Robert R. Alfano; Stavros G. Demos, Editor(s)

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