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Proceedings Paper

Advanced laser system for 3D optoacoustic tomography of the breast
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Paper Abstract

We describe the ongoing development and performance of a high-pulse-energy wavelength-cycling laser system for three-dimensional optoacoustic tomography of the breast. Joule-level energies are desired for achieving the required penetration depths while maintaining safe fluence levels. Wavelength cycling provides a pulse sequence which repeatedly alternates between two wavelengths (approximately 756 and 797 nm) that provide differential imaging. This improves co-registration of captured differential images and quantification of blood oxygen saturation. New design features have been developed for and incorporated into a clinical prototype laser system, to improve efficacy and ease of use in the clinic. We describe the benefits of these features for operation with a clinical pilot optoacoustic / ultrasound dual-modality three-dimensional imaging system.

Paper Details

Date Published: 29 March 2016
PDF: 14 pages
Proc. SPIE 9708, Photons Plus Ultrasound: Imaging and Sensing 2016, 97085B (29 March 2016); doi: 10.1117/12.2209398
Show Author Affiliations
Marc Klosner, Light Age, Inc. (United States)
Gary Chan, Light Age, Inc. (United States)
Chunbai Wu, Light Age, Inc. (United States)
Donald F. Heller, Light Age, Inc. (United States)
Richard Su, Tomowave Labs. (United States)
Sergey Ermilov, Tomowave Labs. (United States)
Hans Peter Brecht, Tomowave Labs. (United States)
Vassili Ivanov, Tomowave Labs. (United States)
Pratik Talole, Tomowave Labs. (United States)
Yang Lou, Washington Univ. at St. Louis (United States)
Mark Anastasio, Washington Univ. at St. Louis (United States)
Alexander Oraevsky, Tomowave Labs. (United States)


Published in SPIE Proceedings Vol. 9708:
Photons Plus Ultrasound: Imaging and Sensing 2016
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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