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Proceedings Paper

Light intensity matching between different intravascular optical coherence tomography systems
Author(s): Shengnan Liu; Jeroen Eggermont; Shimpei Nakatani; Boudewijn P. F. Lelieveldt; Jouke Dijkstra
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Paper Abstract

Currently two commercial intravascular optical coherence tomography (IVOCT) systems are available: Illumien Optis from St. Jude Medical (SJM) and Lunawave from Terumo. Both systems store the light intensity data in a raw vendor specific polar format. However, whereas SJM uses 16-bits per pixel Terumo uses 8-bits meaning the intensity values are in different ranges. This complicates quantitative light intensity based analysis when comparing results based on data from both systems. Therefore, this work aims to find an intensity transformation function from Terumo’s 8-bit OFDI data to SJM’s 16-bit range. The data consists of 8 pullbacks, 4 acquired with each system in the same arteries of 2 different patents pre- and post-stenting implantation. A total of 133 matching sections without stent struts from the two sets of pullbacks were identified based on landmarks such as side-branches and calcified regions. Since the main region of interest in the image is the tissue region only the pixels within 2mm behind the lumen border are used. In order to match the SJM data range, the Terumo data was rescaled and cumulative distribution functions (CDF) were calculated based on the histogram distributions. Comparing these CDFs, the transformation function can be determined. Application of this transformation function not only improves the visual similarity of matching slices it can also be used for further quantitative analysis.

Paper Details

Date Published: 29 February 2016
PDF: 7 pages
Proc. SPIE 9689, Photonic Therapeutics and Diagnostics XII, 96893D (29 February 2016); doi: 10.1117/12.2209311
Show Author Affiliations
Shengnan Liu, Leiden Univ. Medical Ctr. (Netherlands)
Jeroen Eggermont, Leiden Univ. Medical Ctr. (Netherlands)
Shimpei Nakatani, Sakurabashi Watanabe Hospital (Japan)
Boudewijn P. F. Lelieveldt, Leiden Univ. Medical Ctr. (Netherlands)
Delft Univ. of Technology (Netherlands)
Jouke Dijkstra, Leiden Univ. Medical Ctr. (Netherlands)


Published in SPIE Proceedings Vol. 9689:
Photonic Therapeutics and Diagnostics XII
Hyun Wook Kang; Guillermo J. Tearney; Melissa C. Skala; Bernard Choi; Andreas Mandelis; Brian J. F. Wong; Justus F. Ilgner; Nikiforos Kollias; Paul J. Campagnola; Kenton W. Gregory; Laura Marcu; Haishan Zeng, Editor(s)

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