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Proceedings Paper

Design of a portable wide field of view GPU-accelerated multiphoton imaging system for real-time imaging of breast surgical specimens
Author(s): Michael G. Giacomelli; Tadayuki Yoshitake; Lennart Husvogt; Lucas Cahill; Osman Ahsen; Hilde Vardeh; Yury Sheykin; Beverly E. Faulkner-Jones; Joachim Hornegger; Jeff Brooker; Alex Cable; James L. Connolly; James G. Fujimoto
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Paper Abstract

We present a portable multiphoton system designed for evaluating centimeter-scale surgical margins on surgical breast specimens in a clinical setting. The system is designed to produce large field of view images at a high frame rate, while using GPU processing to render low latency, video-rate virtual H&E images for real-time assessment. The imaging system and virtual H&E rendering algorithm are demonstrated by imaging unfixed human breast tissue in a clinical setting.

Paper Details

Date Published: 14 March 2016
PDF: 6 pages
Proc. SPIE 9712, Multiphoton Microscopy in the Biomedical Sciences XVI, 97121G (14 March 2016); doi: 10.1117/12.2209241
Show Author Affiliations
Michael G. Giacomelli, Massachusetts Institute of Technology (United States)
Tadayuki Yoshitake, Massachusetts Institute of Technology (United States)
Lennart Husvogt, Friedrich-Alexander Univ. Erlangen-Nürnberg (Germany)
Lucas Cahill, Massachusetts Institute of Technology (United States)
Osman Ahsen, Massachusetts Institute of Technology (United States)
Hilde Vardeh, Beth Israel Deaconess Medical Ctr., Harvard Medical School (United States)
Yury Sheykin, Beth Israel Deaconess Medical Ctr., Harvard Medical School (United States)
Beverly E. Faulkner-Jones, Beth Israel Deaconess Medical Ctr., Harvard Medical School (United States)
Joachim Hornegger, Friedrich-Alexander Univ. Erlangen-Nürnberg (Germany)
Jeff Brooker, Thorlabs, Inc. (United States)
Alex Cable, Thorlabs, Inc. (United States)
James L. Connolly, Beth Israel Deaconess Medical Ctr., Harvard Medical School (United States)
James G. Fujimoto, Massachusetts Institute of Technology (United States)


Published in SPIE Proceedings Vol. 9712:
Multiphoton Microscopy in the Biomedical Sciences XVI
Ammasi Periasamy; Peter T. C. So; Karsten König, Editor(s)

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