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Proceedings Paper

Lorentz force megahertz optical coherence elastography
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Paper Abstract

Optical Coherence Elastography (OCE) is a rapidly developing technique for assessing tissue biomechanical properties. This study demonstrates the first use of the Lorentz force to induce elastic waves within tissue to quantify the elasticity of tissue in combination with a phase-sensitive OCE system at ~1.5 million A-scans per second. The feasibility of this technique was tested on tissue-mimicking agar phantoms of various concentrations. The results as assessed by OCE were in good agreement with standard mechanical testing of the samples. After the preliminary experiments, the stiffness of porcine liver was examined. The results demonstrate that Lorentz force MHz OCE can be applied to study the elasticity of biological tissue effectively and has the potential for clinical applications due to rapid excitation and imaging.

Paper Details

Date Published: 9 March 2016
PDF: 5 pages
Proc. SPIE 9710, Optical Elastography and Tissue Biomechanics III, 97100D (9 March 2016); doi: 10.1117/12.2209145
Show Author Affiliations
Chen Wu, Univ. of Houston (United States)
Manmohan Singh, Univ. of Houston (United States)
Zhaolong Han, Univ. of Houston (United States)
Raksha Raghunathan, Univ. of Houston (United States)
Chih-Hao Liu, Univ. of Houston (United States)
Jiasong Li, Univ. of Houston (United States)
Alexander Schill, Univ. of Houston (United States)
Kirill V. Larin, Univ. of Houston (United States)
Samara State Aerospace Univ. (Russian Federation)
Baylor College of Medicine (United States)

Published in SPIE Proceedings Vol. 9710:
Optical Elastography and Tissue Biomechanics III
Kirill V. Larin; David D. Sampson, Editor(s)

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