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Proceedings Paper

A miniaturized optoelectronic system for rapid quantitative label-free detection of harmful species in food
Author(s): Ioannis Raptis; Konstantinos Misiakos; Eleni Makarona; Alexandros Salapatas; Panagiota Petrou; Sotirios Kakabakos; Athanasios Botsialas; Gerhard Jobst; Willem Haasnoot; Amadeo Fernandez-Alba; Michelle Lees; Evangelos Valamontes
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Paper Abstract

Optical biosensors have emerged in the past decade as the most promising candidates for portable, highly-sensitive bioanalytical systems that can be employed for in-situ measurements. In this work, a miniaturized optoelectronic system for rapid, quantitative, label-free detection of harmful species in food is presented. The proposed system has four distinctive features that can render to a powerful tool for the next generation of Point-of-Need applications, namely it accommodates the light sources and ten interferometric biosensors on a single silicon chip of a less-than-40mm2 footprint, each sensor can be individually functionalized for a specific target analyte, the encapsulation can be performed at the wafer-scale, and finally it exploits a new operation principle, Broad-band Mach-Zehnder Interferometry to ameliorate its analytical capabilities. Multi-analyte evaluation schemes for the simultaneous detection of harmful contaminants, such as mycotoxins, allergens and pesticides, proved that the proposed system is capable of detecting within short time these substances at concentrations below the limits imposed by regulatory authorities, rendering it to a novel tool for the near-future food safety applications.

Paper Details

Date Published: 22 April 2016
PDF: 7 pages
Proc. SPIE 9725, Frontiers in Biological Detection: From Nanosensors to Systems VIII, 97250A (22 April 2016); doi: 10.1117/12.2209077
Show Author Affiliations
Ioannis Raptis, National Ctr. for Scientific Research Demokritos (Greece)
Konstantinos Misiakos, National Ctr. for Scientific Research Demokritos (Greece)
Eleni Makarona, National Ctr. for Scientific Research Demokritos (Greece)
Alexandros Salapatas, National Ctr. for Scientific Research Demokritos (Greece)
Panagiota Petrou, National Ctr. for Scientific Research Demokritos (Greece)
Sotirios Kakabakos, National Ctr. for Scientific Research Demokritos (Greece)
Athanasios Botsialas, ThetaMetrisis S.A. (Greece)
Gerhard Jobst, Jobst Technologies GmbH (Germany)
Willem Haasnoot, Wageningen Univ. (Netherlands)
Amadeo Fernandez-Alba, Univ. de Almería (Spain)
Michelle Lees, Eurofins Analytics France SAS (France)
Evangelos Valamontes, Technological Educational Institute of Athens (Greece)


Published in SPIE Proceedings Vol. 9725:
Frontiers in Biological Detection: From Nanosensors to Systems VIII
Benjamin L. Miller; Brian T. Cunningham, Editor(s)

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