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Proceedings Paper

Optical topography guided semi-three-dimensional diffuse optical tomography for a multi-layer model of occipital cortex: a pilot methodological study
Author(s): Hao Ding; Yao Zhang; Jie He; Huijuan Zhao; Feng Gao
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Paper Abstract

In this paper, an optical topography (OT) guided diffuse optical tomography (DOT) scheme is developed for functional imaging of the occipital cortex. The method extends the previously proposed semi-three-dimensional DOT methodology to reconstruction of two-dimensional extracerebral and cerebral images using a visual cortex oriented five-layered slab geometry, and incorporate the OT localization regularization in the cerebral reconstruction to achieve enhanced quantitative accuracy and spatial resolution. We validate the methodology using simulated data and demonstrate its merits in comparison to the standalone OT and DOT.

Paper Details

Date Published: 8 March 2016
PDF: 9 pages
Proc. SPIE 9690, Clinical and Translational Neurophotonics; Neural Imaging and Sensing; and Optogenetics and Optical Manipulation, 96901S (8 March 2016); doi: 10.1117/12.2209002
Show Author Affiliations
Hao Ding, Tianjin Univ. (China)
Yao Zhang, Tianjin Univ. (China)
Jie He, Tianjin Univ. (China)
Huijuan Zhao, Tianjin Univ. (China)
Tianjin Key Lab. of Biomedical Detecting Techniques and Instruments (China)
Feng Gao, Tianjin Univ. (China)
Tianjin Key Lab. of Biomedical Detecting Techniques and Instruments (China)


Published in SPIE Proceedings Vol. 9690:
Clinical and Translational Neurophotonics; Neural Imaging and Sensing; and Optogenetics and Optical Manipulation
Steen J. Madsen; E. Duco Jansen; Samarendra K. Mohanty; Nitish V. Thakor; Qingming Luo; Victor X. D. Yang, Editor(s)

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