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Proceedings Paper

Fluorophore-conjugated antibodies for imaging and resection of GI tumors
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Paper Abstract

Negative surgical margins are critical to prevent recurrence in cancer surgery. This is because with current technology in many cases negative margins are impossible due the inability of the surgeon to detect the margin. Our laboratory has developed fluorophore-labeled monoclonal antibodies to aid in cancer visualization in orthotopic nude mouse models of human gastrointestinal (GI) cancer in order to achieve negative margins in fluorescence-guided surgery (FGS). The technologies described herein have the potential to change the paradigm of surgical oncology to engender significantly improved outcomes.

Paper Details

Date Published: 4 March 2016
PDF: 14 pages
Proc. SPIE 9696, Molecular-Guided Surgery: Molecules, Devices, and Applications II, 96960O (4 March 2016); doi: 10.1117/12.2208811
Show Author Affiliations
Michael Bouvet, Univ. of California, San Diego (United States)
AntiCancer, Inc. (United States)
Robert M. Hoffman, Univ. of California, San Diego (United States)
AntiCancer, Inc. (United States)


Published in SPIE Proceedings Vol. 9696:
Molecular-Guided Surgery: Molecules, Devices, and Applications II
Brian W. Pogue; Sylvain Gioux, Editor(s)

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