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Proceedings Paper

A wearable optical device for continuous monitoring during neoadjuvant chemotherapy infusions
Author(s): Fei Teng; Timothy Cormier; Alexis Sauer-Budge; Darren M. Roblyer
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Paper Abstract

We present a new continuous-wave (CW) wearable diffuse optical device aimed at investigating the hemodynamic response of locally advanced breast cancer patients during a patient’s first neoadjuvant chemotherapy infusion. The system consists of a flexible substrate that supports an array of surface-mount LED and photodiode pairs (i.e. optodes). Probe performance was evaluated using solid tissue-simulating phantoms. Measurements revealed high SNR (65dB), low source-detector crosstalk (-59 dB), high measurement precision (0.17%), and good thermal stability (0.2% Vrms/°C). A cuff occlusion experiment was performed on the forearm of a healthy volunteer to demonstrate the ability to track rapid hemodynamic changes.

Paper Details

Date Published: 4 March 2016
PDF: 5 pages
Proc. SPIE 9715, Optical Diagnostics and Sensing XVI: Toward Point-of-Care Diagnostics, 97150P (4 March 2016); doi: 10.1117/12.2208438
Show Author Affiliations
Fei Teng, Boston Univ. (United States)
Timothy Cormier, Boston Univ. (United States)
Alexis Sauer-Budge, Boston Univ. (United States)
Darren M. Roblyer, Boston Univ. (United States)

Published in SPIE Proceedings Vol. 9715:
Optical Diagnostics and Sensing XVI: Toward Point-of-Care Diagnostics
Gerard L. Coté, Editor(s)

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