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Proceedings Paper

Confocal microscopy via multimode fibers: fluorescence bandwidth
Author(s): Damien Loterie; Demetri Psaltis; Christophe Moser
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Paper Abstract

We recently described a method for confocal reflection imaging through fibers, as a way to increase contrast when imaging unstained biological specimens. Using a transmission matrix, focused spots can be created at the distal end of a fiber. The backscattered field coming back from the sample can be filtered using optical correlation to obtain spatial selectivity in the detection. In this proceedings article, we briefly review the working principle of this method, and we discuss how the scheme could be adapted to confocal fluorescence imaging. In particular, we show simulations of the achievable detection bandwidth when using step-index multimode fibers as imaging devices.

Paper Details

Date Published: 15 March 2016
PDF: 6 pages
Proc. SPIE 9717, Adaptive Optics and Wavefront Control for Biological Systems II, 97171C (15 March 2016); doi: 10.1117/12.2208017
Show Author Affiliations
Damien Loterie, École Polytechnique Fédérale de Lausanne (Switzerland)
Demetri Psaltis, École Polytechnique Fédérale de Lausanne (Switzerland)
Christophe Moser, École Polytechnique Fédérale de Lausanne (Switzerland)


Published in SPIE Proceedings Vol. 9717:
Adaptive Optics and Wavefront Control for Biological Systems II
Thomas G. Bifano; Joel Kubby; Sylvain Gigan, Editor(s)

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